{"id":16204,"date":"2026-08-08T18:08:13","date_gmt":"2026-08-08T16:08:13","guid":{"rendered":"https:\/\/aromexperten.se\/what-is-eurycomanone-marker-compound-in-tongkat-ali\/"},"modified":"2026-08-08T18:08:13","modified_gmt":"2026-08-08T16:08:13","slug":"what-is-eurycomanone-marker-compound-in-tongkat-ali","status":"publish","type":"post","link":"https:\/\/aromexperten.se\/en\/what-is-eurycomanone-marker-compound-in-tongkat-ali\/","title":{"rendered":"What is eurycomanone? Marker compound in Tongkat Ali"},"content":{"rendered":"<div class=\"cornerstone-article eurycomanone-guide\">\n<p class=\"article-lead\">\n<strong>What is eurycomanone?<\/strong> It is a naturally occurring plant compound that researchers have identified in <em>Eurycoma longifolia<\/em>, the plant commonly known as Tongkat Ali. The compound belongs to the quassinoids and is used, among other things, as a chemical marker compound in quality control of certain Tongkat Ali extracts.\n<\/p>\n<div class=\"table-of-contents\">\n<strong>Contents<\/strong><\/p>\n<ul>\n<li><a href=\"#vad-ar-eurycomanone\">What is eurycomanone?<\/a><\/li>\n<li><a href=\"#analysmarkor\">Why is the compound used as a marker compound?<\/a><\/li>\n<li><a href=\"#analys\">How do laboratories analyse the compound?<\/a><\/li>\n<li><a href=\"#standardisering\">Standardization and analytical values<\/a><\/li>\n<li><a href=\"#physta\">The marker compound in Physta\u00ae<\/a><\/li>\n<li><a href=\"#coa\">How do you read the value in a COA?<\/a><\/li>\n<li><a href=\"#faq\">Frequently asked questions<\/a><\/li>\n<\/ul>\n<\/div>\n<section id=\"vad-ar-eurycomanone\">\n<h2>What is eurycomanone?<\/h2>\n<p>\nThe compound is a quassinoid that occurs naturally in <em>Eurycoma longifolia<\/em>. Researchers have identified several quassinoids in the plant, and this compound is one of the most commonly used chemical markers when analysing root material and extracts.\n<\/p>\n<p>\nLaboratories primarily use the marker to describe parts of the raw material\u2019s chemical profile. However, on its own it does not provide a complete picture of product quality. Origin, plant part, extraction method, and other analyses also play an important role.\n<\/p>\n<p>\nA scientific review of <em>Eurycoma longifolia<\/em> describes both the plant\u2019s chemical components and various analytical methods. You can read <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9850716\/\" target=\"_blank\" rel=\"noopener noreferrer\">the review on PubMed Central<\/a>.\n<\/p>\n<\/section>\n<figure class=\"article-image\">\n<p><img decoding=\"async\" src=\"https:\/\/aromexperten.se\/wp-content\/uploads\/Tongkat-Ali-Physta.webp\" alt=\"What is eurycomanone \u2013 marker compound in Tongkat Ali Physta\" loading=\"lazy\"><figcaption>\nTongkat Ali Physta\u00ae is a standardized water extract in which several defined quality parameters are analysed.<br \/>\n<\/figcaption><\/figure>\n<section id=\"analysmarkor\">\n<h2>Why is the compound used as a marker compound?<\/h2>\n<p>\nA marker compound is a chemical component that a laboratory can identify and measure. This allows the producer to verify a raw material against established specifications.\n<\/p>\n<p>\nFor Tongkat Ali, this quassinoid is particularly useful because laboratories can analyse it using established chromatographic methods. In addition, it is repeatedly referenced in the scientific literature on <em>Eurycoma longifolia<\/em>.\n<\/p>\n<div class=\"information-box\">\n<p>\n<strong>In short:<\/strong> the analytical value serves as a measurable quality parameter. However, a single chemical marker should not be used as the sole measure of the quality of a botanical raw material.\n<\/p>\n<\/div>\n<\/section>\n<section id=\"analys\">\n<h2>How do laboratories analyse the compound?<\/h2>\n<p>\nLaboratories use, among other things, chromatographic methods to separate and measure different components in a sample. HPLC, high-performance liquid chromatography, is an example of a method that researchers have used when analysing Tongkat Ali.\n<\/p>\n<p>\nFirst, the laboratory prepares the sample. The analytical equipment then separates different chemical compounds. Finally, the analyst compares the results with a reference to identify and quantify the marker in question.\n<\/p>\n<p>\nResearchers have, for example, combined HPLC with other methods to examine the identity and chemical profile of commercial Tongkat Ali products. The study is published via <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6130542\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed Central<\/a>.\n<\/p>\n<\/section>\n<section id=\"standardisering\">\n<h2>Standardization and analytical values<\/h2>\n<p>\nStandardization means that the producer defines specifications for one or more quality parameters. The producer then analyses each production batch and compares the result with these limit values.\n<\/p>\n<p>\nA standardized extract can therefore use several analytical parameters at the same time. As a result, the documentation often provides a broader picture than a single measured value.\n<\/p>\n<p>\nThis differs from a ratio extract. A ratio such as 100:1 describes the relationship between plant material and finished extract, but does not automatically state the content of a specific chemical marker.\n<\/p>\n<p>\nIf you would like to understand the difference in more detail, please read our guide on <a href=\"https:\/\/aromexperten.se\/en\/tongkat-ali-powder-or-extract-differences-explained\/\">Tongkat Ali powder or extract<\/a>.\n<\/p>\n<\/section>\n<section id=\"physta\">\n<h2>The marker compound in Physta\u00ae<\/h2>\n<p>\nPhysta\u00ae is a standardized water extract from the root of <em>Eurycoma longifolia<\/em>. The manufacturer checks several defined quality parameters for each production batch.\n<\/p>\n<p>\nFor this raw material, these include, among other things, the quassinoid in question together with glycosaponins, polysaccharides, and total protein fraction. This means the standardization is not based on a single parameter.\n<\/p>\n<div class=\"information-box\">\n<p>\n<strong>Current batch TA 2506105<\/strong>\n<\/p>\n<ul>\n<li>Measured value: <strong>0.87%<\/strong><\/li>\n<li>Established specification: <strong>0.8\u20131.5%<\/strong><\/li>\n<\/ul>\n<\/div>\n<p>\nThe result applies only to the current production batch. Future batches may therefore show different values within the established specification.\n<\/p>\n<p>\nYou can read more about the extract in our guide <a href=\"https:\/\/aromexperten.se\/en\/what-is-physta-standardization-coa-and-tongkat-ali\/\">What is Physta\u00ae?<\/a>. There we also explain the water extraction, the standardization, and other batch documentation.\n<\/p>\n<p>\nYou can also view the <a href=\"https:\/\/aromexperten.se\/en\/shop\/botanicals\/tongkat-ali-eurycoma-longifolia\/tongkat-ali-physta\/\">current Tongkat Ali Physta\u00ae product and batch information<\/a>.\n<\/p>\n<\/section>\n<section id=\"coa\">\n<h2>How do you read the analytical value in a COA?<\/h2>\n<p>\nA Certificate of Analysis (COA) summarizes laboratory results for a specific production batch. Therefore, it is important to first check that the document\u2019s batch number matches the product in question.\n<\/p>\n<div class=\"table-scroll\">\n<table>\n<thead>\n<tr>\n<th>Term<\/th>\n<th>Meaning<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Specification<\/td>\n<td>The range or limit value established by the producer<\/td>\n<\/tr>\n<tr>\n<td>Result<\/td>\n<td>The value shown by the analysis for the current batch<\/td>\n<\/tr>\n<tr>\n<td>Batch number<\/td>\n<td>Identifies the production run to which the document applies<\/td>\n<\/tr>\n<tr>\n<td>Analytical method<\/td>\n<td>States which method the laboratory used<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\nFor a standardized raw material, the producer therefore compares the measured result with the relevant specification. This makes it possible to verify whether the batch meets the established criteria.\n<\/p>\n<p>\nSee the <a href=\"https:\/\/aromexperten.se\/wp-content\/uploads\/Certificate-of-Analysis-TA2506105.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Certificate of Analysis for Physta\u00ae batch TA 2506105<\/a>.\n<\/p>\n<\/section>\n<section id=\"faq\">\n<h2>Frequently asked questions<\/h2>\n<h3>Is eurycomanone the same thing as Tongkat Ali?<\/h3>\n<p>\nNo. Tongkat Ali is the common name for the plant species <em>Eurycoma longifolia<\/em>. The chemical compound is only one of many components that may occur in the plant material.\n<\/p>\n<h3>Is the compound found in all Tongkat Ali products?<\/h3>\n<p>\nChemical composition can vary between raw materials and products. Among other things, origin, plant material, and processing affect the final profile. In addition, different producers may use different analytical methods and specifications.\n<\/p>\n<h3>Does a higher analytical value automatically mean better quality?<\/h3>\n<p>\nNo. A higher value does not automatically mean higher overall quality. For a standardized extract, it is more relevant to check whether the current batch meets the product\u2019s established specification and what other documentation is available.\n<\/p>\n<h3>Why does Physta\u00ae analyse multiple parameters?<\/h3>\n<p>\nBotanical raw materials consist of many different components. Therefore, the producer checks several defined parameters instead of describing the extract using only a single chemical marker.\n<\/p>\n<h3>Where can I read more about the plant itself?<\/h3>\n<p>\nIn our guide <a href=\"https:\/\/aromexperten.se\/en\/what-is-tongkat-ali-guide-to-eurycoma-longifolia\/\">What is Tongkat Ali?<\/a> we cover <em>Eurycoma longifolia<\/em>, its origin, botany, and different raw material forms.\n<\/p>\n<\/section>\n<aside class=\"important-notice\">\n<h2>About the information<\/h2>\n<p>\nThis article describes the compound from a botanical, analytical, and quality perspective. The information does not describe medical use, treatment, or biological effect.\n<\/p>\n<\/aside>\n<section class=\"sources\">\n<h2>Sources and Further Reading<\/h2>\n<ul>\n<li>\n<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9850716\/\" target=\"_blank\" rel=\"noopener noreferrer\"><br \/>\nScientific review of Eurycoma longifolia, chemical components, and analysis<br \/>\n<\/a>\n<\/li>\n<li>\n<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6130542\/\" target=\"_blank\" rel=\"noopener noreferrer\"><br \/>\nStudy of commercial Tongkat Ali products, including HPLC analysis<br \/>\n<\/a>\n<\/li>\n<li>\n<a href=\"https:\/\/efsa.onlinelibrary.wiley.com\/doi\/10.2903\/j.efsa.2021.6937\" target=\"_blank\" rel=\"noopener noreferrer\"><br \/>\nEFSA\u2019s scientific opinion on a standardized water extract of Eurycoma longifolia<br \/>\n<\/a>\n<\/li>\n<\/ul>\n<\/section>\n<div class=\"cta-box\">\n<h2>Read more about Tongkat Ali and Physta\u00ae<\/h2>\n<p>\nExplore <a href=\"https:\/\/aromexperten.se\/en\/what-is-tongkat-ali-guide-to-eurycoma-longifolia\/\">the plant and its origin<\/a>, read about <a href=\"https:\/\/aromexperten.se\/en\/what-is-physta-standardization-coa-and-tongkat-ali\/\">the standardization of Physta\u00ae<\/a>, or view the <a href=\"https:\/\/aromexperten.se\/en\/shop\/botanicals\/tongkat-ali-eurycoma-longifolia\/tongkat-ali-physta\/\">current Physta\u00ae batch and analytical documentation<\/a>.\n<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>What is eurycomanone? It is a naturally occurring plant compound that researchers have identified in Eurycoma longifolia, the plant commonly known as Tongkat Ali. The compound belongs to the quassinoids and is used, among other things, as a chemical marker compound in quality control of certain Tongkat Ali extracts. Contents What is eurycomanone? Why is [&#8230;]\n","protected":false},"author":1,"featured_media":16205,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[254],"tags":[],"class_list":["post-16204","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-botanicals"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What is eurycomanone? Marker compound in Tongkat Ali | Aromexperten<\/title>\n<meta name=\"description\" content=\"What is eurycomanone? 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